{"schema_version":1,"experiment_id":"eoa_inverse_innovation_exp06_four_proposal_generalization60_20260803","source_assessment_id":"layer_decay_and_expiration_management__physics:P4:v0","cell_id":"layer_decay_and_expiration_management__physics","proposal_index":4,"qualification":"EMPIRICAL_PARTNER_CANDIDATE","criteria":{"specific_differentiated_claim":{"status":"YES","reason":"The proposal retains a falsifiable incremental claim: a specimen-and-aliquot mass-balance ledger combined with scientific-dependency and final-aliquot vetoes, expiring reserve holds, differentiated archive/quarantine states, and disposition tombstones will reveal decision-relevant cases missed by keep-all and campaign-level closeout without producing unsafe handling recommendations."},"credible_problem_signal":{"status":"YES","reason":"The sealed evaluation documents storage-driven disposal of scientifically useful irradiated specimens and an operating irradiated-material archive facing growing-inventory, tracking, retrieval, pedigree, and indefinite-retention challenges."},"identifiable_partner_or_adopter":{"status":"YES","reason":"A licensed irradiated-material specimen bank such as the evaluated NSUF/INL class is a concrete adopter with custodial, scientific, radiological-protection, records, and waste-disposition roles capable of granting access and adjudicating the workflow."},"partner_access_is_necessary":{"status":"YES","reason":"The decisive uncertainties concern proprietary campaign records, historical aliquot lineage and mass balances, actual scientific dependencies, blinded expert disposition judgments, and controlled retrieval performance; these cannot be resolved through further public research."},"safe_authorized_first_step":{"status":"YES","reason":"The first step is a read-only shadow study under existing partner authority, using surrogate retrieval and only already-authorized record-level or visual verification. It excludes opening, moving, assaying, relabeling, transferring, or disposing of controlled specimens and leaves official records unchanged."},"bounded_decisive_empirical_design":{"status":"YES","reason":"A pre-registered study of one closed campaign containing 100–300 specimens compares the proposed lifecycle with keep-all and campaign-level closeout on identity reconciliation, mass conflicts, dependency recall, final-aliquot conflicts, false disposal flags, reviewer agreement, retrieval performance, and review time, with explicit falsification thresholds."},"no_material_negative_gate":{"status":"YES","reason":"All substantive pipeline gates are YES, including problem support, adopter credibility, incremental testability, bounded evidence, and safety/authority. Cost scope is uncertain rather than materially negative and can be measured within the partnered study."},"not_merely_more_research":{"status":"YES","reason":"The next step specifies a partner class, campaign size, required records and personnel, comparators, primary measures, prohibited actions, and conditions that would falsify the intervention."}},"uncertainty_types":["PROBLEM_PREVALENCE","ADOPTER_PULL","INCREMENTAL_EFFECT","WORKFLOW_FIT","DATA_ACCESS","COST_SCOPE"],"partner_profile":"A licensed operator or custodian of an irradiated-material specimen bank with one closed campaign containing intact parent specimens, partially consumed samples, derived aliquots, reserve candidates, and closeout candidates, plus scientific, custody, data, radiological-protection, records, transfer, and waste-disposition personnel authorized to participate.","required_access":"Read-only access to accession, irradiation, measurement, assay, publication or analysis-dependency, custody, remaining-mass, aliquot-lineage, hold, and disposition records for one closed campaign; access to relevant staff for blinded adjudication; surrogate packages; and permission for already-authorized record-level or visual container verification without changing custody or handling state.","bounded_empirical_test":"Pre-register and execute an 8–12 week read-only shadow study over approximately 100–300 specimens and aliquots. Team A constructs the proposed identity, remaining-mass, lineage, dependency, hold, and lifecycle ledger. A blinded scientific, custody, waste, and radiological panel classifies the same set using existing practice. Compare both outputs with keep-all and campaign-level closeout, and test retrieval using surrogates plus only already-authorized record-level or visual verification. Make no physical or official-record changes.","success_condition":"A decision-usable majority of identities, lineage relationships, and remaining masses is reconciled; the proposed workflow finds additional valid dependencies or lifecycle distinctions versus campaign-level closeout, protects all known-required and final-aliquot material, maintains or improves reviewer agreement and retrieval reconnection, produces no unsafe or unvetoed false-disposal recommendation, and yields measurable review-time and cost data.","falsification_condition":"Falsify the intervention if lineage or mass cannot be reconciled for a decision-usable majority, any known-required specimen is classified for disposal without an effective veto, dependency recall is no better than campaign-level closeout, reviewer agreement deteriorates materially, retrieval cannot reconnect containers to metadata, or the workflow produces no decision-relevant distinction beyond existing controls.","rationale":"This is a narrow empirical-partner case: credible external evidence establishes the problem and a capable adopter class, while adjacent prior art leaves a specific integrated claim unresolved. The remaining questions require proprietary specimen-level data, authorized domain adjudication, and bounded retrieval exercises. The proposed shadow study is safe, comparator-based, reversible, and capable of either demonstrating incremental decision value or falsifying the intervention."}