{"schema_version":1,"experiment_id":"eoa_inverse_innovation_exp06_four_proposal_generalization60_20260803","cell_id":"catalytic_pathway_enablement__nanotechnology","portfolio_valid":true,"proposal_assessments":[{"proposal_index":1,"complete":true,"causally_faithful":true,"materially_distinct":true,"reason":"Operationally specifies the nucleation transformation, immobilized reusable facilitator, feed interface, matched controls, turnover, selectivity, saturation and poisoning monitors, regeneration, retirement, authority, rollback, and falsifiers. Its causal path is repeated precursor nucleation through a retained physical interface, distinct from the other three opportunities."},{"proposal_index":2,"complete":true,"causally_faithful":true,"materially_distinct":true,"reason":"Operationally specifies eligible CAD-to-recipe conversion, a reusable versioned compiler, semantic intake, selective routing, independent release, counterfactual testing, multi-case turnover, calibration refresh, deactivation, and safety controls. It preserves the catalytic cycle through reusable informational state rather than added engineering capacity."},{"proposal_index":3,"complete":true,"causally_faithful":true,"materially_distinct":true,"reason":"Operationally specifies controlled deagglomeration, a retained acoustic transducer, bounded feed and residence conditions, whole-output and mass-balance controls, matched sham and current-protocol baselines, repeated turnover, cleaning, cooling, readiness testing, and retirement. Its mechanical dispersion pathway is independent of synthesis, recipe compilation, and institutional handoff."},{"proposal_index":4,"complete":true,"causally_faithful":true,"materially_distinct":true,"reason":"Operationally specifies assay-admissible handoff qualification, a standing reusable broker service, semantic contracting, objective eligibility, independent acceptance, capacity and fairness governance, measured multi-case turnover, relationship and staff regeneration, suspension, appeal, and rollback. It faithfully instantiates the bounded human-institutional catalyst variant without treating staff as inexhaustible."}],"pairwise_assessments":[{"proposal_a":1,"proposal_b":2,"same_problem":false,"same_intervention":false,"independent_opportunity":true,"key_difference":"Proposal 1 lowers a physicochemical nucleation barrier in precursor aliquots with an immobilized surface; proposal 2 lowers repeated design-interpretation and recipe-setup burdens with a calibrated software compiler."},{"proposal_a":1,"proposal_b":3,"same_problem":false,"same_intervention":false,"independent_opportunity":true,"key_difference":"Proposal 1 initiates formation of new nanocrystal seeds at a nanoporous nucleation interface; proposal 3 separates agglomerates in already synthesized suspensions through acoustic microstreaming and device restoration."},{"proposal_a":1,"proposal_b":4,"same_problem":false,"same_intervention":false,"independent_opportunity":true,"key_difference":"Proposal 1 transforms chemical precursor aliquots through a material catalytic interface; proposal 4 transforms samples and records into qualified interfacility handoffs through reusable relationships, templates, and specialist coordination."},{"proposal_a":2,"proposal_b":3,"same_problem":false,"same_intervention":false,"independent_opportunity":true,"key_difference":"Proposal 2 converts digital nanofabrication designs into validated lithography recipes via informational automation; proposal 3 physically converts agglomerated suspensions into assay-ready dispersions via an acoustic flow cell."},{"proposal_a":2,"proposal_b":4,"same_problem":false,"same_intervention":false,"independent_opportunity":true,"key_difference":"Proposal 2 addresses technical recipe construction through deterministic compilation and calibration; proposal 4 addresses cross-organizational trust, interpretation, evidence, and custody through a governed human-institutional broker."},{"proposal_a":3,"proposal_b":4,"same_problem":false,"same_intervention":false,"independent_opportunity":true,"key_difference":"Proposal 3 alters nanoparticle dispersion state through acoustic energy transfer in a reusable device; proposal 4 leaves material structure unchanged and accelerates assay admission through qualification, translation, and custody coordination."}],"replacement_indices":[],"rationale":"Every proposal is operationally complete and preserves the archetype's defining causal structure: an already feasible recurring transformation, a specific barrier, a selective reusable facilitator, explicit interface and capacity limits, counterfactual validation, multi-cycle turnover, regeneration or replacement, and safeguards against side paths and unauthorized standard changes. Across all six pairs, the affected problems, interventions, and causal paths differ materially; none is merely a renamed variant, added feature, narrower population, or implementation detail of another."}