{"schema_version":1,"experiment_id":"eoa_inverse_innovation_exp06_four_proposal_generalization60_20260803","cell_id":"predictive_residual_processing__nanotechnology","portfolio_valid":true,"proposal_assessments":[{"proposal_index":1,"complete":true,"causally_faithful":true,"materially_distinct":true,"reason":"Operationally specifies a scoped layout-conditioned SEM predictor, signed spatial residual, precision gate, synchronized reconstruction, governed offline updates, independent raw-tile audits, explicit missingness, fallback triggers, authority, falsifiers, and an equal-capacity evidence test. Its affected problem and inspection-review pathway are distinct from the other proposals."},{"proposal_index":2,"complete":true,"causally_faithful":true,"materially_distinct":true,"reason":"Implements the archetype through command-derived efference-copy cancellation: predicted self-generated probe response is subtracted from measured waveforms, and the unexplained interaction residual drives bounded-latency supervision. It includes reconstruction, uncertainty weighting, synchronization, raw audits, protected full-signal interlocks, fallback, offline updating, authority, and falsification tests."},{"proposal_index":3,"complete":true,"causally_faithful":true,"materially_distinct":true,"reason":"Defines a reconstructive predictive codec for parallel nanopore currents, with per-pore baseline prediction, signed waveform residuals, cross-pore capacity allocation, buffered event-window retrieval, model synchronization, full-state anchors, independent raw audits, fallback, controlled adaptation, authority, and comparative tests. This is a distinct array-readout opportunity."},{"proposal_index":4,"complete":true,"causally_faithful":true,"materially_distinct":true,"reason":"Defines a hierarchical predictive loop for evolving quantum-dot spectra: wavelength-level residuals unresolved by measurement uncertainty become evidence about kinetic regimes and update a bounded posterior. Synchronized reconstruction, raw-spectrum audits, full-data fallback, reviewed offline revision, chemist authority, falsifiers, and an equal-budget evaluation make it complete and distinct."}],"pairwise_assessments":[{"proposal_a":1,"proposal_b":2,"same_problem":false,"same_intervention":false,"independent_opportunity":true,"key_difference":"Proposal 1 predicts SEM imagery from design layout to prioritize fabrication-defect review; proposal 2 predicts sensory consequences from outgoing probe commands and cancels them to expose external tip-sample interactions for low-latency protection. Their causal paths begin with different predictors and terminate in different decisions."},{"proposal_a":1,"proposal_b":3,"same_problem":false,"same_intervention":false,"independent_opportunity":true,"key_difference":"Proposal 1 suppresses expected spatial layout imagery in a wafer-inspection queue, whereas proposal 3 codes temporal open-pore current against synchronized per-pore predictors and retrieves buffered translocation windows across an acquisition array. Image-defect review and multichannel assay readout are independently adoptable problems and interventions."},{"proposal_a":1,"proposal_b":4,"same_problem":false,"same_intervention":false,"independent_opportunity":true,"key_difference":"Proposal 1 compares a fabricated SEM tile with a layout-conditioned expected image to route local defects; proposal 4 compares evolving spectra with a recipe-conditioned hierarchical kinetic model so persistent spectral residuals revise trajectory-regime belief and prompt chemist review."},{"proposal_a":2,"proposal_b":3,"same_problem":false,"same_intervention":false,"independent_opportunity":true,"key_difference":"Proposal 2 uses an efference copy of actuator commands to remove self-generated mechanical response for probe safety; proposal 3 has no command-cancellation loop and instead uses stochastic open-current prediction, residual coding, and event-buffer retrieval to preserve nanopore translocations under shared readout constraints."},{"proposal_a":2,"proposal_b":4,"same_problem":false,"same_intervention":false,"independent_opportunity":true,"key_difference":"Proposal 2 separates externally caused force or deflection from command-induced probe response on a control timescale; proposal 4 hierarchically separates spectral measurement variation from sustained reaction-trajectory mismatch and updates uncertainty over chemical kinetic regimes without actuating the reactor."},{"proposal_a":3,"proposal_b":4,"same_problem":false,"same_intervention":false,"independent_opportunity":true,"key_difference":"Proposal 3 is a per-pore reconstructive transport codec for sparse blockade events against a near-stationary electrical baseline; proposal 4 is hierarchical batch supervision for distributed wavelength-and-time departures from a changing reaction trajectory, with Bayesian regime updating and chemist review."}],"replacement_indices":[],"rationale":"All four proposals are operationally complete and preserve the archetype's essential model-prediction-comparison-residual-routing-reconstruction-update loop together with synchronization, independent raw audits, explicit error budgets, safety bypasses, and full-signal fallback. Every pair differs materially in the affected bottleneck, domain intervention, initiating prediction source, residual semantics, downstream decision, actors, equipment, and adoption boundary; none is merely a renamed variant, feature addition, population restriction, or implementation detail of another."}