{"closest_prior_art":[{"name":"Via-Cell Bioaerosol Sampling Cassette","overlap":"A disposable mold-sampling cassette preserves viable bioaerosols, supports direct-microscopy prescreening, and permits subsequent culture, PCR, or other analysis.","remaining_difference":"It does not disclose a predeclared multi-site family, paired specimens with an inaccessible confirmation mate, a family-size-adjusted promotion threshold, attempt tabs, blinded confirmation, or action-governing status tags.","source_ids":["SRC4"]},{"name":"ASTM D7789-21 surface-swab practice","overlap":"Standardizes sterile collection of fungal material and allows microscopy, culture, biochemical analysis, or combinations of methods to distinguish fungal from non-fungal surface material.","remaining_difference":"It does not reserve an independently sealed mate, correct promotion thresholds for the number of sites, preserve every attempted look mechanically, or govern consequential decisions through staged physical status.","source_ids":["SRC3"]},{"name":"EPA professional mold-sampling guidance","overlap":"Recognizes surface sampling as potentially useful, stresses expert protocol design and interpretation, and notes the absence of federal mold or spore limits.","remaining_difference":"It supplies interpretive safeguards but no cassette, multiplicity adjustment, holdout specimen, blinded viability confirmation, or physical claim registry.","source_ids":["SRC2"]}],"contrastive_claim_falsifier":"The remaining contrast would be falsified by an opened product, standard, or documented practice that already combines a predeclared numbered multi-site mold-sampling family, immediate paired-specimen separation with an inaccessible mate, a promotion threshold calibrated to family size, and blinded orthogonal viability confirmation before consequential action. Operationally, it would also fail if the proposed seeded-coupon trial showed no lower batch-level false-promotion rate, compromised holdouts, or frequent confirmed sterile sites despite valid controls.","contrastive_claim_remaining":"The bounded search found adjacent fungal cassettes, standardized surface sampling, prescreen-to-culture workflows, and professional interpretation guidance, but not their combination with a material inventory of every site, family-size-dependent promotion, a prospectively sealed biological holdout, blinded orthogonal viability testing, and status-gated authority review.","experiment_id":"eoa_inverse_innovation_exp13_second_slot_policy60_20260806","gates":{"adequate_source_search":{"rationale":"Searches covered the exact title and intervention, archive mold and mould terminology, ATP and swab screening, split or duplicate specimens, bioaerosol cassettes, standards, culture and microscopy, and familywise-error terminology. Exactly four relevant sources from four publishers were opened, including official guidance, a standard, and a product source.","source_ids":["SRC1","SRC2","SRC3","SRC4"],"status":"PASS"},"bounded_next_test":{"rationale":"The proposed inert-coupon bench comparison is finite, measurable, uses predeclared family sizes and controls, avoids collection contact, and can estimate false promotions, sensitivity, contamination, seal integrity, and blinded confirmation agreement without authorizing operational action.","source_ids":["SRC2","SRC3","SRC4"],"status":"PASS"},"distinct_testable_claim":{"rationale":"The family-size comparator plus mechanically registered attempts and prospectively sealed orthogonal holdout is distinguishable from the located single-sample cassette and ordinary multi-method swab practice, and its effect can be tested at the batch level.","source_ids":["SRC3","SRC4"],"status":"PASS"},"no_obvious_safety_or_authority_stop":{"rationale":"No obvious stop prevents non-destructive validation on inert coupons. Professional oversight, PPE, moisture response, controls, and the prohibition on changing access or treatment from validation results are consistent with the sources' cautions; independent visible or occupational hazards must continue to govern precautions.","source_ids":["SRC1","SRC2","SRC3"],"status":"PASS"},"supported_problem":{"rationale":"Official preservation guidance establishes rapid mold risk after water damage, EPA warns that mold sampling lacks federal limits and requires expert interpretation, and ASTM identifies non-fungal materials that sampling must distinguish. These support a real interpretation problem, although the search did not directly document archive incidents in which a many-site extreme alone caused closure or treatment.","source_ids":["SRC1","SRC2","SRC3"],"status":"PASS"}},"prior_art_disposition":"ADJACENT_PRIOR_ART","problem_evidence":{"finding":"Post-water mold risk, costly salvage, ambiguous surface material, and the need for careful sampling interpretation are visible. Existing standards and products support microscopy, culture, biochemical analysis, and prescreening, but direct evidence that archive responders routinely select the maximum among dozens of rapid readings without multiplicity correction was not located in this bounded search.","source_ids":["SRC1","SRC2","SRC3","SRC4"],"status":"PARTLY_SUPPORTED"},"research_id":"eoa_inverse_innovation_exp13_light_screen_20260806","schema_version":1,"screen_id":"E13P049","screen_survival":true,"search_lanes":{"component_combination":{"no_result_note":"No result disclosed the complete combination of a multi-site physical registry, family-size comparator, sealed paired holdout, and blinded viability confirmation.","queries":["mold sampling split sample duplicate blind confirmation culture microscopy","bioaerosol cassette split specimen sealed duplicate sample mold confirmation","mold surface sampling multiple testing familywise false positive Bonferroni"],"source_ids":["SRC3","SRC4"]},"direct_problem_and_intervention":{"no_result_note":"The exact proposal title produced no match; searches returned adjacent mold-sampling and preservation practices.","queries":["\"Split-Specimen Mold Confirmation Cassette\"","archive library post water leak mold sampling fluorescence ATP swab active mold guidance","mold environmental sampling many samples false positive multiple comparisons threshold"],"source_ids":["SRC1","SRC2","SRC3","SRC4"]},"products_practices_and_standards":{"no_result_note":null,"queries":["ASTM mold assessment sampling surface culture microscopy standard","library archives mold water emergency response sampling remediation guidelines","ATP fluorescence mold surface screening active mold false positive residue"],"source_ids":["SRC1","SRC2","SRC3","SRC4"]},"synonyms_and_historical_terms":{"no_result_note":null,"queries":["archive mould mildew water ingress sampling active dormant viability culture microscopy","\"mold\" \"split sample\" environmental sampling laboratory confirmation","mold sampling cassette paired media tamper evident blind sample culture microscopy"],"source_ids":["SRC1","SRC3","SRC4"]}},"sources":[{"claims_supported":["Water-damaged archive and library material can develop mold rapidly under warm, humid, poorly ventilated conditions.","Salvage requires safety coordination, planning, inventory, and written or photographic records.","Mold growth can increase recovery and restoration costs."],"publisher":"U.S. National Archives and Records Administration","source_id":"SRC1","source_type":"OFFICIAL_GUIDANCE","title":"Salvage of Water Damaged Library Materials – Part 3","url":"https://www.archives.gov/preservation/conservation/library-materials-03.html"},{"claims_supported":["Visible mold generally does not require sampling.","No EPA or other federal mold-spore limits exist for compliance determinations.","Sampling protocols and result interpretation should be handled by experienced professionals, and disturbing hidden mold can release spores."],"publisher":"U.S. Environmental Protection Agency","source_id":"SRC2","source_type":"OFFICIAL_GUIDANCE","title":"Is Sampling/Testing for Mold Necessary?","url":"https://www.epa.gov/mold/samplingtesting-mold-necessary"},{"claims_supported":["Sterile swabs are an established method for collecting fungal surface material.","Samples may be analyzed by direct microscopy, culture, biochemical analysis, or combinations thereof.","Surface sampling can help distinguish fungal material from stains, soot, dust, adhesives, and other non-fungal material."],"publisher":"ASTM International","source_id":"SRC3","source_type":"OFFICIAL_STANDARD","title":"ASTM D7789-21: Standard Practice for Collection of Fungal Material from Surfaces by Swab","url":"https://store.astm.org/d7789-21.html"},{"claims_supported":["A disposable bioaerosol cassette can preserve viable and non-viable mold material for transport.","One collected sample can support direct-microscopy prescreening and subsequent culture, PCR, or other analysis.","The product is adjacent cassette-based prior art but does not describe an independently sealed paired holdout or family-size threshold."],"publisher":"Electron Microscopy Sciences","source_id":"SRC4","source_type":"FIRST_PARTY_PRODUCT","title":"Via-Cell Bioaerosol Sampling Cassette","url":"https://www.emsdiasum.com/via-cell-bioaerosol-sampling-cassette"}],"world_novelty_boundary":"This bounded public-web screen found adjacent prior art but cannot establish world novelty, patentability, market size, expert acceptance, or realized value. Unindexed patents, paywalled standards, internal institutional procedures, laboratory protocols, and products described under different terminology may contain closer matches."}