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Bioinformatics

← Back to Domain-Specific Abstractions by Domain

3 domain-specific abstractions whose origin domain is Bioinformatics.

  • Gap Penalty — Score a sequence alignment by charging for maximal insertion/deletion runs according to their opening, length, position, or context, so gaps compete explicitly with matches and substitutions.
  • Sequence feature variant type — A typed annotation describing how a protein sequence variation alters a defined structural or functional sequence feature.
  • THEMATICS — Predict enzyme active-site residues from clusters of computed ionizable groups whose theoretical microscopic titration curves deviate from ordinary Henderson–Hasselbalch behavior.