Molecular Evolution

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2 domain-specific abstractions whose origin domain is Molecular Evolution.

• Ka/Ks ratio — Compare nonsynonymous substitutions per nonsynonymous site with synonymous substitutions per synonymous site to summarize selective constraint or episodic positive selection under an explicit codon-evolution model.
• Substitution Model — A phylogenetic probability model that assigns rates or probabilities to changes among a finite set of biological character states along evolutionary branches, converting branch duration into transition probabilities for likelihood, distance, simulation, and ancestral inference.