Effect of dependent errors in the assessment of diagnostic or screening test accuracy when the reference standard is imperfect.¶
Walter, S. D., Macaskill, P., Lord, S. J., & Irwig, L. (2012). Effect of dependent errors in the assessment of diagnostic or screening test accuracy when the reference standard is imperfect. Statistics in Medicine, 31(11), 1129-1138.
Cited by¶
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Primes¶
- Ground Truth
- And there is a recognition of ground-truth-as-construct: the reference channel is itself produced by some procedure — a human labeller, a biopsy, a survey instrument — and is subject to its own error structure, which propagates into all derived scores.
This sourceShows a reference standard is itself a fallible construct whose error (and its dependence structure) propagates as bias into every derived accuracy estimate.
Supported in partVerified against the publisher's abstract
Abstract: an imperfect reference standard must often be used, and bias in apparent sensitivity, specificity and overall accuracy is derived — the claim's frame, for diagnostic tests only, not surveys or labelling.
“When no gold standard is available to evaluate a diagnostic or screening test, as is often the case, an imperfect reference standard test must be used instead. Furthermore, the errors of the test and its reference standard may not be independent.”
- And there is a recognition of ground-truth-as-construct: the reference channel is itself produced by some procedure — a human labeller, a biopsy, a survey instrument — and is subject to its own error structure, which propagates into all derived scores.
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