The Neutral Theory of Molecular Evolution¶
Kimura, M. (1983). The Neutral Theory of Molecular Evolution. Cambridge University Press.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Selection-Visibility Gate
- With s = −0.10 and p = 0.02, the realized coefficient is −0.002, which in a population of moderate size falls below the drift barrier: A is effectively neutral, and its frequency wanders on demographic noise rather than on its consequence.
This sourceEstablishes the drift barrier: a variant whose realized selection coefficient is small relative to the effective population size behaves as effectively neutral.
Supported in partVerified against the publisher's abstract
The book's publisher abstract asserts only that most molecular change is caused by random drift of selectively neutral mutants; it does not state the s = -0.10, p = 0.02 arithmetic or the drift-barrier threshold.
“The theory - which asserts that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants - has caused controversy ever since.”
- With s = −0.10 and p = 0.02, the realized coefficient is −0.002, which in a population of moderate size falls below the drift barrier: A is effectively neutral, and its frequency wanders on demographic noise rather than on its consequence.
Verification¶
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Registry ID ref:07b9285dfa92 · see in the full table