Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution¶
Han, X., & Boyden, E. S. (2007). Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution. PLOS ONE.
Cited by¶
1 citation across 1 artifact.
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Domain-specific¶
- Photostimulation
- Han and Boyden demonstrated a related conditional two-color arrangement in neurons expressing both ChR2 and a light-driven halorhodopsin: the different effectors support depolarizing and hyperpolarizing responses under different illumination, rather than one channel reversing its effect solely because the wavelength changes.
This sourceOriginal experimental paper; author-hosted full PDF at https://edboyden.org/07.03.han.pdf. Used for conditional ChR2/halorhodopsin two-color control, not wavelength-only sign reversal.
- Han and Boyden demonstrated a related conditional two-color arrangement in neurons expressing both ChR2 and a light-driven halorhodopsin: the different effectors support depolarizing and hyperpolarizing responses under different illumination, rather than one channel reversing its effect solely because the wavelength changes.
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