Parameter and Structural Identifiability Concepts and Ambiguities¶
Cobelli, C., & DiStefano, J. J. (1980). Parameter and Structural Identifiability Concepts and Ambiguities: A Critical Review and Analysis. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 239(1).
Cited by¶
1 citation across 1 artifact.
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Mechanisms¶
- Compartmental PK/PD Model
- More compartments capture multiphasic curves but risk parameters that are guessed rather than identified from sparse data.
This sourceDefines identifiability as whether unique parameter values can be obtained from dynamic experiment data and warns that ambiguities can persist even in simple models.
- More compartments capture multiphasic curves but risk parameters that are guessed rather than identified from sparse data.
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Registry ID ref:0b61bea399bc · see in the full table