Reducing Inappropriate Polypharmacy¶
Scott, I. A., Hilmer, S. N., Reeve, E., Potter, K., Le Couteur, D., Rigby, D., Gnjidic, D., et al. (2015). Reducing Inappropriate Polypharmacy: The Process of Deprescribing. JAMA Internal Medicine, 175(5), 827-834.
Cited by¶
1 citation across 1 artifact.
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Primes¶
- Intervention Stack Accretion
- A primary-care patient makes the accretion concrete: starting at 55 on one antihypertensive, each subsequent year adds a medication — a statin, an SSRI, a PPI to treat reflux triggered by the antihypertensive, a benzo for SSRI-induced insomnia, an analgesic, a second antihypertensive for pressure elevated under the analgesic's renal effects — until by 75 the patient is on 11 medications,
This sourceEstablishes deprescribing as the distinct named inverse-operation for accreted polypharmacy, including prescribing cascades where one drug treats another drug's side effect.
- A primary-care patient makes the accretion concrete: starting at 55 on one antihypertensive, each subsequent year adds a medication — a statin, an SSRI, a PPI to treat reflux triggered by the antihypertensive, a benzo for SSRI-induced insomnia, an analgesic, a second antihypertensive for pressure elevated under the analgesic's renal effects — until by 75 the patient is on 11 medications,
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