The Genetics of Inbreeding Depression.¶
Charlesworth, D., & Willis, J. H. (2009). The Genetics of Inbreeding Depression. Nature Reviews Genetics, 10(11), 783-796.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Diversification
- Communications: frequency, spatial, and time diversity in fading channels, where multiple non-coherent paths combine to reduce outage probability even when each path's signal-to-noise is unchanged. Supply chain: multi-sourcing, where dual-sourcing reduces correlated supply-shock exposure via the correlation-weighted variance reduction. Organisational design: high-reliability organisations structure overlapping roles to be functionally uncorrelated, the literature on common-mode failure resting on the diversification insight. Genetics: heterozygosity and hybrid vigour buffer against allele-specific selection pressure at the genome scale.
This sourceReviews heterozygosity and heterosis as buffering against allele-specific deleterious effects.
Supported in partVerified against the publisher's abstract
The abstract ties heterosis and heterozygote advantage to masking of recessive deleterious mutations, but never speaks of allele-specific selection pressure at the genome scale.
“Classical genetic studies and modern molecular evolutionary approaches now suggest that inbreeding depression and heterosis are predominantly caused by the presence of recessive deleterious mutations in populations.”
- Communications: frequency, spatial, and time diversity in fading channels, where multiple non-coherent paths combine to reduce outage probability even when each path's signal-to-noise is unchanged. Supply chain: multi-sourcing, where dual-sourcing reduces correlated supply-shock exposure via the correlation-weighted variance reduction. Organisational design: high-reliability organisations structure overlapping roles to be functionally uncorrelated, the literature on common-mode failure resting on the diversification insight. Genetics: heterozygosity and hybrid vigour buffer against allele-specific selection pressure at the genome scale.
Verification¶
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Registry ID ref:0f0f67294f33 · see in the full table