Data Monitoring in Clinical Trials¶
DeMets, D. L., Furberg, C. D., & Friedman, L. M. (2006). Data Monitoring in Clinical Trials: A Case Studies Approach. Springer.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Mechanisms¶
- Stop-or-Scale-Back Gate
- The discipline that keeps it honest is to fix the criteria before operation and before the data, to give the monitoring to a party that does not benefit from continuing, and to log and review every override so an eroding gate stays visible.
This sourceTreats interim stopping criteria as matters to be specified before data accumulate and monitored by an independent data monitoring committee.
- The discipline that keeps it honest is to fix the criteria before operation and before the data, to give the monitoring to a party that does not benefit from continuing, and to log and review every override so an eroding gate stays visible.
Verification¶
Does it exist? Confirmed. This work's DOI resolves to a registered record, which fixes its identity. That is all it fixes.
Does it back the claim? Not recorded. The single citation of this work carries no recorded support check.
Support is checked per citation rather than per work — the same source can be cited soundly in one article and wrongly in another. Per-citation recording began recently, so a citation with no recorded check is a gap in the record rather than evidence it went unchecked.
See how references were verified.
Registry ID ref:11692e0ec1a2 · see in the full table