Molecular Biology of the Cell¶
Alberts, B., Johnson, A., Lewis, J., Morgan, D., Raff, M., Roberts, K., & Walter, P. (2014). Molecular Biology of the Cell. Molecular Biology of the Cell.
Cited by¶
11 citations across 11 artifacts.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Asymmetric Flux
- In biology and biochemistry it is cell-membrane semipermeability, gated ion channels, active transport pumps, osmotic systems, the blood-brain barrier, and respiratory countercurrent exchange.
This sourceDescribes selective membrane transport — semipermeability, gated ion channels, active pumps — as the cellular instance of directional flux control.
- In biology and biochemistry it is cell-membrane semipermeability, gated ion channels, active transport pumps, osmotic systems, the blood-brain barrier, and respiratory countercurrent exchange.
- Context
- In biology and genetics, gene expression is regulated by cellular context — the same gene drives different programs in different tissues, and the "same" mutation can be benign in one genetic background and lethal in another.
This sourceStandard reference on context-dependent gene regulation: the same gene drives different programs across cell types, and mutation effects depend on genetic background.
- In biology and genetics, gene expression is regulated by cellular context — the same gene drives different programs in different tissues, and the "same" mutation can be benign in one genetic background and lethal in another.
- Fungibility
- In biology and chemistry, reagents are fungible within purity classes and ATP molecules are fungible metabolic currency — the substrate-level instance of the same pattern.
This sourceEstablishes ATP as the universal energy currency of the cell — any ATP molecule substitutes for any other to power cellular work — the substrate-level instance of fungibility.
- In biology and chemistry, reagents are fungible within purity classes and ATP molecules are fungible metabolic currency — the substrate-level instance of the same pattern.
- Injectivity
- In biology it is DNA replication preserving sequence identity per daughter chromosome, and the structural lesson that the protein-to-mRNA back-map fails precisely because the codon map is degenerate rather than injective.
This sourceStandard text establishing semiconservative DNA replication preserving sequence identity and the degeneracy of the genetic code (which makes the protein-to-mRNA back-map non-injective).
- In biology it is DNA replication preserving sequence identity per daughter chromosome, and the structural lesson that the protein-to-mRNA back-map fails precisely because the codon map is degenerate rather than injective.
- Local Sequence Legality
- Molecular biology: DNA codon legality (start and stop codons in reading frame), restriction-site avoidance in synthetic biology, and splice-site signals at exon–intron boundaries.
This sourceThe genetic code, reading frame, start/stop codons, and splice-site signals as local legality rules on a nucleotide alphabet, independent of whether the product is useful.
- Molecular biology: DNA codon legality (start and stop codons in reading frame), restriction-site avoidance in synthetic biology, and splice-site signals at exon–intron boundaries.
- Minimum-Necessary Disclosure
- Journalistic source protection — reporters strip identifying detail before publication; the projection sits with the publisher, not the reader. Audit-log access scoping — auditors receive the slice relevant to their engagement; the operator's projection is authoritative. Biological selectivity — cell membranes and the blood-brain barrier project what passes outward; the receiving compartment does not filter what has already arrived.
This sourceDescribes selective permeability of cell membranes and the blood-brain barrier — source-side control of what passes outward, with the receiving compartment not filtering what has arrived.
- Journalistic source protection — reporters strip identifying detail before publication; the projection sits with the publisher, not the reader. Audit-log access scoping — auditors receive the slice relevant to their engagement; the operator's projection is authoritative. Biological selectivity — cell membranes and the blood-brain barrier project what passes outward; the receiving compartment does not filter what has already arrived.
- Permeability
- Cell biology and physiology: membrane permeability to ions, water, and metabolites determines what enters and leaves a cell, with selectivity from lipid-bilayer thickness plus channel proteins plus transporters.
This sourceStandard reference on membrane permeability to ions, water, and metabolites: lipid bilayers are highly impermeable to charged molecules, crossing occurring via channels and transporters.
- Cell biology and physiology: membrane permeability to ions, water, and metabolites determines what enters and leaves a cell, with selectivity from lipid-bilayer thickness plus channel proteins plus transporters.
- Potentiation
- Immunology and vaccination: Priming of memory lymphocytes during initial antigen exposure, resulting in enhanced secondary response upon re-exposure—faster, larger antibody production, higher-affinity antibodies through somatic hypermutation, and class-switch to more potent isotypes (IgG, IgA), as Alberts and colleagues (2014) detail in their canonical cellular immunology treatment.
This sourceGarland Science. Standard cell-biology reference: documents receptor synthesis, trafficking, surface expression, and density regulation as the molecular basis for capacity scaling — the cellular mechanism by which biological systems address saturation through increased receptor abundance rather than higher ligand concentration.
- Immunology and vaccination: Priming of memory lymphocytes during initial antigen exposure, resulting in enhanced secondary response upon re-exposure—faster, larger antibody production, higher-affinity antibodies through somatic hypermutation, and class-switch to more potent isotypes (IgG, IgA), as Alberts and colleagues (2014) detail in their canonical cellular immunology treatment.
- Reaction Intermediate
- In molecular biology, mRNA sits between gene and protein, transcribed and then degraded, its concentration regulated independently of both DNA and protein.
This sourceCanonical text describing mRNA as the transcribed-then-degraded intermediate between gene and protein, regulated independently of both.
- In molecular biology, mRNA sits between gene and protein, transcribed and then degraded, its concentration regulated independently of both DNA and protein.
- Receptor Saturation
- As Alberts et al. (2014) describe for receptor synthesis, trafficking, and abundance regulation in Molecular Biology of the Cell,
This sourceGarland Science. Standard cell-biology reference: documents receptor synthesis, trafficking, surface expression, and density regulation as the molecular basis for capacity scaling — the cellular mechanism by which biological systems address saturation through increased receptor abundance rather than higher ligand concentration.
- As Alberts et al. (2014) describe for receptor synthesis, trafficking, and abundance regulation in Molecular Biology of the Cell,
- Termination Condition
- And in biology, apoptosis terminates cell life on checkpoint failure, telomeres terminate replication, and satiety signals terminate feeding.
This sourceDescribes apoptosis on checkpoint failure and replicative senescence (telomere) limits as biological termination programs.
- And in biology, apoptosis terminates cell life on checkpoint failure, telomeres terminate replication, and satiety signals terminate feeding.
Verification¶
This reference passed the adversarial substantiation pipeline: it was checked to exist and to support the claim it is attached to. See how references were verified.
Links previously used in the corpus¶
Before the registry existed this work was also linked 4 other ways.
- https://www.google.com/books/edition/Molecular_Biology_of_the_Cell/2xIwDwAAQBAJ ×1
- https://www.ncbi.nlm.nih.gov/books/NBK26815/ ×1
- https://www.ncbi.nlm.nih.gov/nlmcatalog/101653884 ×1
- https://www.worldcat.org/title/molecular-biology-of-the-cell/oclc/887505319 ×1
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