The toxicity of poisons applied jointly¶
Bliss, C. I. (1939). The toxicity of poisons applied jointly. Annals of Applied Biology, 26(3), 585-615.
Cited by¶
1 citation across 1 artifact.
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Primes¶
- Synergy and Antagonism
- A pharmacologist's combination-drug analysis transfers to geneticists' epistasis analysis (the additive-genetic-variance baseline and departures from it), to team-production analysis (additive individual contributions vs interaction terms), and to chemical-combination analysis, building on the independence baseline that Bliss (1939) developed for jointly applied poisons.
This sourceOriginal derivation of the independence (Bliss) baseline for combined toxicants; foundational reference establishing the cross-domain pattern of baseline-specification followed by deviation measurement.
- A pharmacologist's combination-drug analysis transfers to geneticists' epistasis analysis (the additive-genetic-variance baseline and departures from it), to team-production analysis (additive individual contributions vs interaction terms), and to chemical-combination analysis, building on the independence baseline that Bliss (1939) developed for jointly applied poisons.
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