Problems of Spectrum and Bias in Evaluating the Efficacy of Diagnostic Tests¶
Ransohoff, D. F., & Feinstein, A. R. (1978). Problems of Spectrum and Bias in Evaluating the Efficacy of Diagnostic Tests. New England Journal of Medicine, 299(17), 926-930.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Mechanisms¶
- Diagnostic Cutoff Revision
- The review states the tradeoff plainly: the revised cutoff avoids ≈X unnecessary workups per thousand tests at the cost of a small, quantified rise in missed early cases — and it must be re-validated on the lab's own patients, because a cutoff that fits a vendor's trial population can misfire on a different one.
This sourceShows that a diagnostic cutoff can misfire when transferred from one patient population to another.
- The review states the tradeoff plainly: the revised cutoff avoids ≈X unnecessary workups per thousand tests at the cost of a small, quantified rise in missed early cases — and it must be re-validated on the lab's own patients, because a cutoff that fits a vendor's trial population can misfire on a different one.
Verification¶
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Does it back the claim? Not recorded. The single citation of this work carries no recorded support check.
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Registry ID ref:16e06b526948 · see in the full table