Preventing the return of fear in humans using reconsolidation update mechanisms¶
Schiller, D., Monfils, M., Raio, C. M., Johnson, D. C., LeDoux, J. E., & Phelps, E. A. (2010). Preventing the return of fear in humans using reconsolidation update mechanisms. Nature, 463(7277), 49-53.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Reconsolidation
- Neuroscience (origin) — a reactivated memory returns to a labile state and can be modified or eliminated during the post-retrieval window, with therapeutic application to PTSD via memory-update treatment.
This sourceShows the reactivation window can be used therapeutically to update a fear memory via reframing (retrieval-extinction) within the labile period.
Supported in partVerified against the publisher's abstract
The abstract backs the retrieval-lability window and a fear-memory update that persisted a year, but says nothing about PTSD; the PTSD clause is extrapolation, not this source's finding.
“We provide evidence that old fear memories can be updated with non-fearful information provided during the reconsolidation window. As a consequence, fear responses are no longer expressed, an effect that lasted at least a year and was selective only to reactivated memories without affecting others.”
- Neuroscience (origin) — a reactivated memory returns to a labile state and can be modified or eliminated during the post-retrieval window, with therapeutic application to PTSD via memory-update treatment.
Verification¶
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Registry ID ref:19a0ee1d66d4 · see in the full table