Novel Proteinaceous Infectious Particles Cause Scrapie

Prusiner, S. B. (1982). Novel Proteinaceous Infectious Particles Cause Scrapie. Science, 216(4542), 136-144.

Type

Journal article

Intellectual base

Primary research

Year

1982

DOI

10.1126/science.6801762

Link

https://doi.org/10.1126/science.6801762

Cited from

chemistry_materials

Cited by

1 citation across 1 artifact.

Each citation links to the sentence it supports in the citing article.

Primes

• Defect
  • In biology and medicine, a point mutation in a critical gene produces macroscopic disease (sickle-cell anaemia), and a single misfolded prion can seed cascade misfolding.

    This sourceIntroduces the prion — a misfolded protein that catalyzes the conversion of normal protein into more copies of the misfolded form, a single misfolded molecule seeding cascade misfolding.

Verification

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Registry ID ref:19eeb512ee57 · see in the full table