Ritonavir¶
Hsu, Granneman, & Bertz. (1998). Ritonavir. Clinical Pharmacokinetics.
Cited by¶
1 citation across 1 artifact.
Domain-specific¶
- Enzyme Induction
- Drug–drug interactions — CYP3A4 induction by rifampicin, phenytoin, carbamazepine, and St John's wort lowers exposure to oral contraceptives, immunosuppressants, and warfarin across unrelated therapeutic areas. Autoinduction — carbamazepine and ritonavir induce the enzymes that metabolize themselves, progressively shortening their own half-life and complicating titration to steady state
Supported in partVerified against the publisher's abstract
“Because of autoinduction, plasma concentrations generally reach steady state 2 weeks after the start of administration.”
- Drug–drug interactions — CYP3A4 induction by rifampicin, phenytoin, carbamazepine, and St John's wort lowers exposure to oral contraceptives, immunosuppressants, and warfarin across unrelated therapeutic areas. Autoinduction — carbamazepine and ritonavir induce the enzymes that metabolize themselves, progressively shortening their own half-life and complicating titration to steady state
Verification¶
Does it exist? Not checked yet. This work's DOI is recorded above but has not been resolved against an external catalogue, so nothing here confirms the work exists.
Does it back the claim? Read against the text for 1 of 1 citation: 1 supported in part. Each verdict is shown under its citation below, with what in the work backs the sentence.
Support is checked per citation rather than per work — the same source can be cited soundly in one article and wrongly in another. Per-citation recording began recently, so a citation with no recorded check is a gap in the record rather than evidence it went unchecked.
See how references were verified.
Registry ID ref:1eb56b04e5b0 · see in the full table