Foodborne Illness Acquired in the United States—Major Pathogens¶
Scallan, E., Hoekstra, R. M., Angulo, F. J., Tauxe, R. V., Widdowson, M., Roy, S. L., Jones, J. L., et al. (2011). Foodborne Illness Acquired in the United States—Major Pathogens. Emerging Infectious Diseases.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Domain-specific¶
- Outbreak Underascertainment
- running from below 1 where a well-ascertained disease is over-reported to one or two orders of magnitude where testing is rationed — with the real-surge-versus-ascertainment-artifact diagnostic doing the core work. Seroprevalence-based burden estimation — antibody surveys supplying the population denominator that estimates the asymptomatic-and-care-seeking layers and recovers the true-to-reported multiplier (the COVID demonstration, where national serosurveys implied a median of roughly 18× more infections than reported cases, with an interquartile range of about 6–39× and far larger ratios in low-testing settings). Foodborne and waterborne outbreak epidemiology — CDC outbreak-multiplier estimates for Salmonella, Campylobacter, and norovirus, each pathogen carrying its characteristic undercount through the same ordered pyramid
This sourceScallan et al. supply the CDC pathogen-specific multipliers - under-diagnosis 29.3 for nontyphoidal Salmonella and 30.3 for Campylobacter - built layer by layer from care-seeking, stool submission, laboratory testing practice and test sensitivity; they are burden multipliers for routine surveillance rather than outbreak multipliers, and norovirus's burden is estimated by a different route in the same paper. Scallan et al. supply the multiplier, the method and the total this sentence states: a 29.3-fold under-diagnosis factor for nontyphoidal Salmonella built from care-seeking, stool-submission, laboratory-testing and test-sensitivity layers, and 9.4 million episodes a year from 31 major pathogens (90% CrI 6.6-12.7 million); the ~48 million headline that follows in the article is this paper plus its companion on unspecified agents, which this one leaves to be estimated elsewhere.
- running from below 1 where a well-ascertained disease is over-reported to one or two orders of magnitude where testing is rationed — with the real-surge-versus-ascertainment-artifact diagnostic doing the core work. Seroprevalence-based burden estimation — antibody surveys supplying the population denominator that estimates the asymptomatic-and-care-seeking layers and recovers the true-to-reported multiplier (the COVID demonstration, where national serosurveys implied a median of roughly 18× more infections than reported cases, with an interquartile range of about 6–39× and far larger ratios in low-testing settings). Foodborne and waterborne outbreak epidemiology — CDC outbreak-multiplier estimates for Salmonella, Campylobacter, and norovirus, each pathogen carrying its characteristic undercount through the same ordered pyramid
Verification¶
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