Canalization of Development and the Inheritance of Acquired Characters.¶
WADDINGTON, C. H. (1942). Canalization of Development and the Inheritance of Acquired Characters. Nature, 150(3811), 563-565.
Cited by¶
4 citations across 4 artifacts.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Functional Redundancy (Degeneracy)
- The genetic code's degeneracy is the canonical biological instance of functional redundancy and a structural realization of what Waddington (1942) called canalization — the buffering of developmental outcomes against genetic and environmental perturbation.
This sourceOriginal formulation of canalization — developmental outcomes buffered against genetic and environmental perturbation; supports framing genetic-code degeneracy as a structural realization of canalization.
Supported in partVerified against the publisher's abstract
Waddington 1942 is the paper that named canalization of development, but its abstract gives no definition of canalization as buffering against perturbation and says nothing about genetic-code degeneracy or functional redundancy.
“It is the purpose of this short communication to suggest that recent views on the nature of the developmental process make it easier to understand how the genotypes of evolving organisms can respond to the environment in a more co-ordinated fashion.”
- The genetic code's degeneracy is the canonical biological instance of functional redundancy and a structural realization of what Waddington (1942) called canalization — the buffering of developmental outcomes against genetic and environmental perturbation.
- Multi Path Convergence
- In developmental biology, canalization absorbs different genetic and environmental perturbations and funnels toward a small set of phenotypic outcomes.
This sourceIntroduces canalization: developmental pathways are buffered so that different genetic and environmental perturbations funnel toward a small set of stable phenotypic outcomes.
- In developmental biology, canalization absorbs different genetic and environmental perturbations and funnels toward a small set of phenotypic outcomes.
- Observable Surface Becomes Contract
- The shared intervention catalogue is recognisable across both: generality clauses in legal drafting (keep the nominal surface narrow), and canalization in biology (buffering that keeps incidental variation from becoming a surface for co-option) are the legal and biological forms of shrink-the-surface, the same structural-engineering move as protocol jitter in software.
This sourceIntroduces canalization — developmental buffering that keeps incidental variation from becoming a surface for co-option.
Supported in partVerified against the publisher's abstract
Waddington 1942 is the right terminus for the term "canalization of development", but the abstract we hold never calls it buffering against "a surface for co-option" and says nothing of the legal or software halves of the claim.
“It is the purpose of this short communication to suggest that recent views on the nature of the developmental process make it easier to understand how the genotypes of evolving organisms can respond to the environment in a more co-ordinated fashion.”
- The shared intervention catalogue is recognisable across both: generality clauses in legal drafting (keep the nominal surface narrow), and canalization in biology (buffering that keeps incidental variation from becoming a surface for co-option) are the legal and biological forms of shrink-the-surface, the same structural-engineering move as protocol jitter in software.
Domain-specific¶
- Genetic Assimilation
- Canalization is robustness of phenotype against perturbation
This sourceThe paper that introduced canalization — developmental buffering as a concept distinct from the plasticity-first historical sequence this entry describes.
Supported in partVerified against the source
- Canalization is robustness of phenotype against perturbation
Verification¶
Does it exist? Confirmed. This work's DOI resolves to a registered record, which fixes its identity. That is all it fixes.
Does it back the claim? Read against the text for 3 of 4 citations: 3 supported in part. Each verdict is shown under its citation below, with what in the work backs the sentence.
Support is checked per citation rather than per work — the same source can be cited soundly in one article and wrongly in another. Per-citation recording began recently, so a citation with no recorded check is a gap in the record rather than evidence it went unchecked.
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Registry ID ref:29ff843082c3 · see in the full table