Canalization of Development and the Inheritance of Acquired Characters.¶
WADDINGTON, C. H. (1942). Canalization of Development and the Inheritance of Acquired Characters. Nature, 150(3811), 563-565.
Cited by¶
4 citations across 4 artifacts.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Functional Redundancy (Degeneracy)
- The genetic code's degeneracy is the canonical biological instance of functional redundancy and a structural realization of what Waddington (1942) called canalization — the buffering of developmental outcomes against genetic and environmental perturbation.
This sourceOriginal formulation of canalization — developmental outcomes buffered against genetic and environmental perturbation; supports framing genetic-code degeneracy as a structural realization of canalization.
- The genetic code's degeneracy is the canonical biological instance of functional redundancy and a structural realization of what Waddington (1942) called canalization — the buffering of developmental outcomes against genetic and environmental perturbation.
- Multi Path Convergence
- In developmental biology, canalization absorbs different genetic and environmental perturbations and funnels toward a small set of phenotypic outcomes.
This sourceIntroduces canalization: developmental pathways are buffered so that different genetic and environmental perturbations funnel toward a small set of stable phenotypic outcomes.
- In developmental biology, canalization absorbs different genetic and environmental perturbations and funnels toward a small set of phenotypic outcomes.
- Observable Surface Becomes Contract
- The shared intervention catalogue is recognisable across both: generality clauses in legal drafting (keep the nominal surface narrow), and canalization in biology (buffering that keeps incidental variation from becoming a surface for co-option) are the legal and biological forms of shrink-the-surface, the same structural-engineering move as protocol jitter in software.
This sourceIntroduces canalization — developmental buffering that keeps incidental variation from becoming a surface for co-option.
- The shared intervention catalogue is recognisable across both: generality clauses in legal drafting (keep the nominal surface narrow), and canalization in biology (buffering that keeps incidental variation from becoming a surface for co-option) are the legal and biological forms of shrink-the-surface, the same structural-engineering move as protocol jitter in software.
Domain-specific¶
- Genetic Assimilation
- Canalization is robustness of phenotype against perturbation
This sourceThe paper that introduced canalization — developmental buffering as a concept distinct from the plasticity-first historical sequence this entry describes.
- Canalization is robustness of phenotype against perturbation
Verification¶
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