Kinetics of distribution of substances administered to the body¶
Teorell, T. (1937). Kinetics of distribution of substances administered to the body. Archives Internationales de Pharmacodynamie et de Thérapie.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Primes¶
- PK/PD Modeling (Pharmacokinetics / Pharmacodynamics)
- The construct manages the complexity of drug-response relationships by decomposing them into PK and PD sub-models, each with interpretable parameters, then reassembling through an explicit coupling — a compartmental decomposition strategy traceable to Teorell (1937) in his foundational analysis of the kinetics of distribution of substances administered to the body.
This sourceFoundational paper introducing compartmental decomposition of drug distribution, the structural decomposition strategy on which all later PK and PK/PD modeling builds.
- The construct manages the complexity of drug-response relationships by decomposing them into PK and PD sub-models, each with interpretable parameters, then reassembling through an explicit coupling — a compartmental decomposition strategy traceable to Teorell (1937) in his foundational analysis of the kinetics of distribution of substances administered to the body.
Verification¶
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Registry ID ref:2a2c623a0fe4 · see in the full table