Efficiency and power in genetic association studies.

de Bakker, P. I. W., Yelensky, R., Pe'er, I., Gabriel, S. B., Daly, M. J., & Altshuler, D. (2005). Efficiency and power in genetic association studies. Nature Genetics, 37(11), 1217-1223.

Type

Journal article

Intellectual base

Primary research

Year

2005

DOI

10.1038/ng1669

Link

https://doi.org/10.1038/ng1669

Cited by

1 citation across 1 artifact.

Domain-specific

• Tag SNP
  • De Bakker and colleagues showed that tag-selection and analysis strategies trade genotyping investment, test burden, and power; multi-marker tests may improve coverage or rare-haplotype sensitivity but can change the multiple-testing and common-variant power balance.

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