Trained Immunity

Netea, M. G., Joosten, L. A. B., Latz, E., Mills, K. H. G., Natoli, G., Stunnenberg, H. G., O’Neill, L. A. J., et al. (2016). Trained Immunity: A Program of Innate Immune Memory in Health and Disease. Science, 352(6284).

Type

Journal article

Intellectual base

Primary research

Year

2016

DOI

10.1126/science.aaf1098

Link

https://doi.org/10.1126/science.aaf1098

Cited from

biology_ecology

Cited by

1 citation across 1 artifact.

Each citation links to the sentence it supports in the citing article.

Primes

• Metaplasticity
  • In the immune system, trained immunity reprograms innate cells to respond more or less strongly to subsequent stimuli.

    This sourceEstablishes trained immunity—innate immune cells reprogrammed by prior stimuli to respond more or less strongly to later challenges, a second-order modulation informing prime-boost schedules.

Verification

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Registry ID ref:3b2024ecbd2f · see in the full table