Drug Interactions with Tobacco Smoking¶

Zevin, & Benowitz. (1999). Drug Interactions with Tobacco Smoking. Clinical Pharmacokinetics.

Type: Journal article
Intellectual base: Primary research
Year: 1999
DOI: 10.2165/00003088-199936060-00004
DOI registrant: Springer Nature
Link: https://doi.org/10.2165/00003088-199936060-00004

Cited by¶

1 citation across 1 artifact.

Domain-specific¶

Enzyme Induction
- . Hepatology and chronic exposure — alcohol up-regulates CYP2E1 (altering acetaminophen and solvent metabolism) and smoking induces CYP1A2 via AhR, lowering caffeine, clozapine, and theophylline
  
  Supported in partVerified against the publisher's abstract
  
  “Polycyclic aromatic hydrocarbons in tobacco smoke are believed to be responsible for the induction of cytochrome P450 (CYP) 1A1, CYP1A2 and possibly CYP2E1.”
  From the publisher's abstract.
  
  Read by an automated reader; not a human review. How support was checked

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