Teratogen update: Angiotensin‐converting enzyme inhibitors¶
Barr, M. (1994). Teratogen update: Angiotensin‐converting enzyme inhibitors: Angiotensin‐converting enzyme inhibitors. Teratology.
Cited by¶
1 citation across 1 artifact.
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Domain-specific¶
- Contraindication
- The same mechanism (angiotensin-converting-enzyme blockade) that helps the typical patient impairs the fetal renin-angiotensin system, causing reduced fetal renal perfusion, oligohydramnios, skull ossification defects, and neonatal renal failure
This sourceThe canonical description of ACE-inhibitor fetopathy: blockade of the fetal renin-angiotensin system produces fetal hypotension and renal hypoperfusion, with oligohydramnios, neonatal renal failure and hypocalvaria following — a second- and third-trimester effect, distinct from the first-trimester malformation question.
SupportedVerified against the source
- The same mechanism (angiotensin-converting-enzyme blockade) that helps the typical patient impairs the fetal renin-angiotensin system, causing reduced fetal renal perfusion, oligohydramnios, skull ossification defects, and neonatal renal failure
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Registry ID ref:419239a0ced0 · see in the full table