The Sensitivity of Single-Strand Conformation Polymorphism Analysis for the Detection of Single Base Substitutions

Sheffield, B., Kwitek, Sandstrom, & Stone. (1993). The Sensitivity of Single-Strand Conformation Polymorphism Analysis for the Detection of Single Base Substitutions.

Type

Unclassified

Intellectual base

Unclassified

Year

1993

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Cited by

1 citation across 1 artifact.

Domain-specific

• Single-strand conformation polymorphism
  • … transfers from Two equal-length fragments differing by one base form distinct folds and appear as different bands on a nondenaturing gel. to A diagnostic interpretation treats a mobility shift as a screening signal requiring controls and confirmatory sequence identification, not as proof of a particular variant..

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