Defining and Improving the Genome-Wide Specificities of CRISPR–Cas9 Nucleases

Tsai, S. Q., & Joung, J. K. (2016). Defining and Improving the Genome-Wide Specificities of CRISPR–Cas9 Nucleases. Nature Reviews Genetics, 300-312.

Type

Journal article

Intellectual base

Primary research

Year

2016

Link

https://pmc.ncbi.nlm.nih.gov/articles/PMC7225572/

Cited by

1 citation across 1 artifact.

Domain-specific

• Surveyor Nuclease Assay
  • A positive result says that cleavable heterogeneity is present at the assayed locus and can give an approximate position or editing fraction; it normally does not reveal the exact nucleotide change, assign each product to an allele, or establish genome-wide specificity.

Verification

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