Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins¶
Costa, & Herz. (1989). Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins. Proceedings of the National Academy of Sciences.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Domain-specific¶
- Inverse Agonist
- Costa and Herz's 1989 study is the seminal demonstration
This sourceA study of delta opioid receptors in NG108-15 cell membranes that distinguishes two types of competitive antagonist. The finding that one type of competitive antagonist exhibits negative intrinsic activity, inhibiting basal GTPase activity rather than merely failing to stimulate the receptor.
Supported in partVerified against the publisher's abstract
“Here we show that for a member of this family of receptors (delta opioid receptors in membranes of NG108-15 neuroblastoma-glioma cells), two types of competitive antagonists can be distinguished.”
- Costa and Herz's 1989 study is the seminal demonstration
Verification¶
Does it exist? Not checked yet. This work's DOI is recorded above but has not been resolved against an external catalogue, so nothing here confirms the work exists.
Does it back the claim? Read against the text for 1 of 1 citation: 1 supported in part. Each verdict is shown under its citation below, with what in the work backs the sentence.
Support is checked per citation rather than per work — the same source can be cited soundly in one article and wrongly in another. Per-citation recording began recently, so a citation with no recorded check is a gap in the record rather than evidence it went unchecked.
See how references were verified.
Registry ID ref:4c07be715635 · see in the full table