A Method for Obtaining and Analyzing Sensitivity Data¶
Dixon, W. J., & Mood, A. M. (1948). A Method for Obtaining and Analyzing Sensitivity Data. Journal of the American Statistical Association, 43(241), 109-126.
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Primes¶
- Empirical No-Failure Anchor
- An engineer reading a toxicology dossier and a toxicologist reading a qualification report can each locate all four without learning the other's units, and that is what makes the pattern portable rather than merely suggestive.
This sourceStates a sensitivity-testing design and estimator purely in terms of ordered challenge levels and a binary pass/fail criterion, with no substrate commitment, and remains the basis of up-and-down dose-finding procedures decades later and in unrelated fields.
- An engineer reading a toxicology dossier and a toxicologist reading a qualification report can each locate all four without learning the other's units, and that is what makes the pattern portable rather than merely suggestive.
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