Definition of metabolism-dependent xenobiotic toxicity with co-cultures of human hepatocytes and mouse 3T3 fibroblasts in the novel integrated discrete multiple organ co-culture (IdMOC) experimental system.

Li, A. P., Uzgare, A., & LaForge, Y. S. (2012). Definition of metabolism-dependent xenobiotic toxicity with co-cultures of human hepatocytes and mouse 3T3 fibroblasts in the novel integrated discrete multiple organ co-culture (IdMOC) experimental system. Chemico-Biological Interactions, 199(1), 1-8.

Type

Journal article

Intellectual base

Primary research

Year

2012

DOI

10.1016/j.cbi.2012.05.003

Link

https://doi.org/10.1016/j.cbi.2012.05.003

Cited by

1 citation across 1 artifact.

Domain-specific

• Integrated Discrete Multiple Organ Co-Culture (IdMOC)
  • This permits questions about direct toxicity, toxicity localized to a metabolizing population, and toxicity mediated by a diffusible metabolite.

Verification

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Registry ID ref:5a30691a3da5 · see in the full table