Synaptic Pruning by Microglia Is Necessary for Normal Brain Development.

Paolicelli, R. C., Bolasco, G., Pagani, F., Maggi, L., Scianni, M., Panzanelli, P., Giustetto, M., et al. (2011). Synaptic Pruning by Microglia Is Necessary for Normal Brain Development. Science, 1456-1458.

Type

Journal article

Intellectual base

Primary research

Year

2011

DOI

10.1126/science.1202529

Link

https://doi.org/10.1126/science.1202529

Cited from

cognitive_science

Cited by

1 citation across 1 artifact.

Each citation links to the sentence it supports in the citing article.

Primes

• Pruning
  • The removal mechanism is microglia-mediated phagocytosis, which physically eliminates the tagged under-used synapses.

    This sourceDemonstrates microglia-mediated phagocytosis as the mechanism physically eliminating under-used synapses.

Verification

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Registry ID ref:5ab92ec3a407 · see in the full table