Overall performance of a drug–drug interaction clinical decision support system¶
Van De Sijpe, G., Quintens, C., Walgraeve, K., Van Laer, E., Penny, J., De Vlieger, G., Schrijvers, R., et al. (2022). Overall performance of a drug–drug interaction clinical decision support system: quantitative evaluation and end-user survey. BMC Medical Informatics and Decision Making, 22.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Conjunctive Path Activation
- The interventions are the prime's: combination-aware monitoring — interaction-checking systems that alert on joint states (this drug plus that drug plus this lab pattern) rather than individual thresholds — and breaking the AND at the most modifiable edge, typically by removing or substituting one of the interacting drugs.
This sourceDrug-drug-interaction clinical-decision-support evaluation showing that incorporating patient-specific data (laboratory values, concomitant medication, demographics) yields fewer but more relevant alerts — alerting on joint drug-plus-lab states rather than single thresholds, the combination-aware monitoring the prime describes.
Supported in partVerified against the publisher's abstract
Van De Sijpe 2022's abstract traces false-positive DDI alerts to a too-broad screening interval and unincorporated patient-specific data such as QTc values, backing the drug-plus-lab half of the claim only.
“False positive alerts were caused by a too broad screening interval and lack of incorporation of patient-specific characteristics, such as QTc values.”
- The interventions are the prime's: combination-aware monitoring — interaction-checking systems that alert on joint states (this drug plus that drug plus this lab pattern) rather than individual thresholds — and breaking the AND at the most modifiable edge, typically by removing or substituting one of the interacting drugs.
Verification¶
Does it exist? Confirmed. This work's DOI resolves to a registered record, which fixes its identity. That is all it fixes.
Does it back the claim? Read against the text for 1 of 1 citation: 1 supported in part. Each verdict is shown under its citation below, with what in the work backs the sentence.
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Registry ID ref:5f38b28331bd · see in the full table