Network Motifs¶
Milo, R., Shen-Orr, S., Itzkovitz, S., Kashtan, N., Chklovskii, D., & Alon, U. (2002). Network Motifs: Simple Building Blocks of Complex Networks. Science, 298(5594), 824-827.
Cited by¶
2 citations across 2 artifacts.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Motif
- Literature and film: thematic motifs (rain, the sea, a recurring colour), structural motifs (descent-and-return), and aural-visual motifs in a director's or composer's corpus. Network science: network motifs — small recurring subgraph patterns (feed-forward loops, bi-fans) whose over- or under-representation relative to a random null model characterises a network's function, with identical reasoning across gene-regulatory, neuronal, social, and hyperlink graphs.
This sourceIntroduces network motifs as small subgraph patterns significantly over-represented relative to randomized networks with the same degree sequence, recurring across gene-regulatory, neuronal, food-web, and other networks.
Supported in partVerified against the publisher's abstract
Abstract supports network motifs as over-represented subgraph patterns across several network types, but not literature/film motifs, under-representation, or identical cross-domain reasoning.
“we defined “network motifs,” patterns of interconnections occurring in complex networks at numbers that are significantly higher than those in randomized networks. We found such motifs in networks from biochemistry, neurobiology, ecology, and engineering.”
- Literature and film: thematic motifs (rain, the sea, a recurring colour), structural motifs (descent-and-return), and aural-visual motifs in a director's or composer's corpus. Network science: network motifs — small recurring subgraph patterns (feed-forward loops, bi-fans) whose over- or under-representation relative to a random null model characterises a network's function, with identical reasoning across gene-regulatory, neuronal, social, and hyperlink graphs.
Mechanisms¶
- Graph Motif Mining Algorithm
- One directed three-node circuit — the feed-forward loop, where a regulator controls a target both directly and through an intermediate
This sourceIdentifies the three-node feed-forward loop as a regulator acting on a target both directly and through an intermediate regulator.
- One directed three-node circuit — the feed-forward loop, where a regulator controls a target both directly and through an intermediate
Verification¶
Does it exist? Confirmed. This work's DOI resolves to a registered record, which fixes its identity. That is all it fixes.
Does it back the claim? Read against the text for 1 of 2 citations: 1 supported in part. Each verdict is shown under its citation below, with what in the work backs the sentence.
Support is checked per citation rather than per work — the same source can be cited soundly in one article and wrongly in another. Per-citation recording began recently, so a citation with no recorded check is a gap in the record rather than evidence it went unchecked.
See how references were verified.
Registry ID ref:6090b6a41366 · see in the full table