The Evolutionary Advantage of Recombination.¶
Felsenstein, J. (1974). The Evolutionary Advantage of Recombination. Genetics, 78(2), 737-756.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Ratchet Effect
- The direction-asymmetric coupling is decisive: the least-loaded class (the genomes carrying the fewest mutations) can be lost by chance drift, but in an asexual lineage there is no mechanism to regenerate it — without recombination, you cannot recombine two moderately-loaded genomes into a less-loaded one.
This sourceCoins the term 'Muller's ratchet' and formalizes it, showing recombination as the unlatching mechanism — the structural argument for why sex persists despite its costs.
Supported in partVerified against the publisher's abstract
Felsenstein's abstract backs the Muller-ratchet half of the claim (deleterious mutants spread without recombination) but does not state the least-loaded-class clause.
“It also predicts the "ratchet mechanism" discovered by Muller, who pointed out that deleterious mutants would more readily increase in a population without recombination.”
- The direction-asymmetric coupling is decisive: the least-loaded class (the genomes carrying the fewest mutations) can be lost by chance drift, but in an asexual lineage there is no mechanism to regenerate it — without recombination, you cannot recombine two moderately-loaded genomes into a less-loaded one.
Verification¶
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Registry ID ref:60ff38931d97 · see in the full table