Blinding in randomised trials¶
Schulz, K. F., & Grimes, D. A. (2002). Blinding in randomised trials: hiding who got what. The Lancet, 359(9307), 696-700.
Cited by¶
2 citations across 2 artifacts.
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Primes¶
- Autonomy
- And in research methodology, blinded protocols enforce the autonomy of data from analyst expectation — the data governed by the measurement procedure rather than the investigator's hypothesis.
This sourceExplains blinding as enforcing the autonomy of data from analyst expectation — the data governed by the measurement procedure rather than the investigator's hypothesis.
- And in research methodology, blinded protocols enforce the autonomy of data from analyst expectation — the data governed by the measurement procedure rather than the investigator's hypothesis.
Mechanisms¶
- Double-Blind Trial Protocol
- Its strength is that it is the most complete guard the archetype offers against both participant expectancy and provider behavior, neutralizing effects like differential attention and the nocebo response in one design.
This sourceExplains that blinding reduces performance and ascertainment biases arising from participant and provider knowledge of treatment allocation.
- Its strength is that it is the most complete guard the archetype offers against both participant expectancy and provider behavior, neutralizing effects like differential attention and the nocebo response in one design.
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