Assessing Human Health Risks of Chemicals

International Programme on Chemical Safety. (1994). Assessing Human Health Risks of Chemicals: Derivation of Guidance Values for Health-Based Exposure Limits (Environmental Health Criteria 170).

Type

Unclassified

Intellectual base

Unclassified

Year

1994

Link

no authoritative link yet

Cited by

1 citation across 1 artifact.

Domain-specific

• NOAEL (No Observed Adverse Effect Level)
  • The structural role of the NOAEL in toxicological risk assessment is as the empirical upper anchor from which acceptable human exposures are derived by dividing by a composite uncertainty factor, typically 100 — a factor of 10 for interspecies extrapolation (rat to human) multiplied by another factor of 10 for intraspecies variation (variation within the human population)

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