Design and analysis of phase I clinical trials¶
Storer, B. E. (1989). Design and analysis of phase I clinical trials. Biometrics, 45(3), 925-937.
Cited by¶
1 citation across 1 artifact.
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Primes¶
- Empirical No-Failure Anchor
- This is one of the few settings where the two-sided bracket is produced by design rather than by luck.
This sourceDescribes escalation designs in which cohorts ascend a dose ladder until toxicity is observed, so the stopping dose and the highest cleared dose are produced together by the design rather than by luck.
- This is one of the few settings where the two-sided bracket is produced by design rather than by luck.
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