The limited in vitro lifetime of human diploid cell strains¶
Hayflick, L. (1965). The limited in vitro lifetime of human diploid cell strains. Experimental Cell Research, 37(3), 614-636.
Cited by¶
1 citation across 1 artifact.
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Primes¶
- Temporal Decay and Degradation
- Inspection protocols from bridge engineering (visual, ultrasonic, thermal imaging) transfer to facilities management and to organizational knowledge assessment (what critical knowledge resides only in retiring staff?), echoing the structurally similar replicative-limit characterization first established for biological cells by Hayflick (1965).
This sourceEstablishes the "Hayflick limit": replicative senescence as a finite, characteristic-curve degradation phenomenon at the cellular level; structurally analogous to maintenance-replacement intervals in engineered systems.
- Inspection protocols from bridge engineering (visual, ultrasonic, thermal imaging) transfer to facilities management and to organizational knowledge assessment (what critical knowledge resides only in retiring staff?), echoing the structurally similar replicative-limit characterization first established for biological cells by Hayflick (1965).
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Registry ID ref:7c01b26f8cdb · see in the full table