ArfGAP1 Responds to Membrane Curvature Through the Folding of a Lipid Packing Sensor Motif

Bigay, J., Casella, J., Drin, G., Mesmin, B., & Antonny, B. (2005). ArfGAP1 Responds to Membrane Curvature Through the Folding of a Lipid Packing Sensor Motif. The EMBO Journal, 24(13), 2244-2253.

Type

Journal article

Intellectual base

Primary research

Year

2005

Volume

24

Issue

13

Pages

2244-2253

DOI

10.1038/sj.emboj.7600714

DOI registrant

Springer Nature

Link

https://doi.org/10.1038/sj.emboj.7600714

Cited by

1 citation across 1 artifact.

Domain-specific

• Amphipathic lipid packing sensor motifs
  • Amphipathic lipid packing sensor motifs are roughly 20-40-residue protein segments that are weakly structured in solution but form an amphipathic alpha helix on defect-rich membranes, placing bulky hydrophobic side chains into exposed lipid-packing defects while polar residues face the aqueous phase.

Verification

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Registry ID ref:7df8bbc6e5fb · see in the full table