Clozapine-Induced Agranulocytosis: Incidence and Risk Factors in the United States¶
Alvir, J. M. (1993). Clozapine-Induced Agranulocytosis: Incidence and Risk Factors in the United States: Incidence and Risk Factors in the United States. New England Journal of Medicine.
Cited by¶
1 citation across 1 artifact.
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Domain-specific¶
- Idiosyncratic Reaction
- Clozapine, the most effective antipsychotic for treatment-resistant schizophrenia, causes agranulocytosis — a dangerous collapse of infection-fighting white cells — in roughly 1% of patients, unpredictably and independent of dose
This sourceReports clozapine's greater effectiveness in refractory schizophrenia alongside a cumulative agranulocytosis incidence of about 0.8-0.9%.
Supported in partVerified against the publisher's abstract
“Clozapine is an atypical antipsychotic agent that is more effective than standard neuroleptic drugs in the treatment of patients with refractory schizophrenia.”
- Clozapine, the most effective antipsychotic for treatment-resistant schizophrenia, causes agranulocytosis — a dangerous collapse of infection-fighting white cells — in roughly 1% of patients, unpredictably and independent of dose
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Registry ID ref:7fff97b0bd22 · see in the full table