Statistical practice in high-throughput screening data analysis¶
Malo, N., Hanley, J. A., Cerquozzi, S., Pelletier, J., & Nadon, R. (2006). Statistical practice in high-throughput screening data analysis. Nature Biotechnology, 167-175.
Cited by¶
1 citation across 1 artifact.
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Mechanisms¶
- Progressive Option Screening
- And because a promising compound can be knocked out early by a quirk of the crude first assay, the team samples the rejected pool and keeps a path to pull a discarded compound back in if a later insight warrants — the false-negative
This sourceShows that a crude first assay can eliminate a promising compound as a false negative.
- And because a promising compound can be knocked out early by a quirk of the crude first assay, the team samples the rejected pool and keeps a path to pull a discarded compound back in if a later insight warrants — the false-negative
Verification¶
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Registry ID ref:82ca27a08d65 · see in the full table