Comparison of Treatment of Renal Calculi by Open Surgery, Percutaneous Nephrolithotomy, and Extracorporeal Shockwave Lithotripsy.¶
Charig, C. R., Webb, D. R., Payne, S. R., & Wickham, J. E. (1986). Comparison of Treatment of Renal Calculi by Open Surgery, Percutaneous Nephrolithotomy, and Extracorporeal Shockwave Lithotripsy. British Medical Journal, 879-882.
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Primes¶
- Simpson–Yule Effect
- In epidemiology and medicine, a treatment can look worse than placebo overall while being better within every severity stratum, because sicker patients were preferentially given the treatment.
This sourceThe kidney-stone case in which open surgery beats percutaneous nephrolithotomy within both stone-size strata yet loses in the pooled rate, because the more invasive treatment was preferentially given to larger (harder) stones — the canonical medical Simpson's-paradox example whose numbers (78% vs 83% pooled; 93%/87% and 73%/69% by stratum) are reproduced in the prime's worked example.
- In epidemiology and medicine, a treatment can look worse than placebo overall while being better within every severity stratum, because sicker patients were preferentially given the treatment.
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