The Predictive Approaches to Treatment Effect Heterogeneity (PATH) Statement.¶
Kent, D. M., Paulus, J. K., van Klaveren, D., D'Agostino, R., Goodman, S., Hayward, R., Ioannidis, J. P. A., et al. (2020). The Predictive Approaches to Treatment Effect Heterogeneity (PATH) Statement. Annals of Internal Medicine, 172(1), 35-45.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Distributional Effects
- In epidemiology and public health, an average treatment effect masks heterogeneity by age, comorbidity, and baseline severity, so the same drug may help the severely affected and harm the mildly affected.
This sourceFramework for heterogeneity of treatment effect, where an average effect conceals subgroup-level benefit and harm.
Supported in partVerified against the publisher's abstract
Supplies the HTE definition — nonrandom variation in the magnitude or direction of a treatment effect across covariate levels — but not the claim's age, comorbidity, or severity examples or its drug-harm illustration.
“Heterogeneity of treatment effect (HTE) refers to the nonrandom variation in the magnitude or direction of a treatment effect across levels of a covariate, as measured on a selected scale, against a clinical outcome.”
- In epidemiology and public health, an average treatment effect masks heterogeneity by age, comorbidity, and baseline severity, so the same drug may help the severely affected and harm the mildly affected.
Verification¶
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Does it back the claim? Read against the text for 1 of 1 citation: 1 supported in part. Each verdict is shown under its citation below, with what in the work backs the sentence.
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