Benchmark Dose Technical Guidance¶
U.S. Environmental Protection Agency. (2012). Benchmark Dose Technical Guidance.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Empirical No-Failure Anchor
- Remove any one of them and what remains is merely a level at which nothing was noticed, which is a far weaker object than it looks.
This sourceStates that the NOAEL is limited to one of the doses included in the study and so is pinned to dose selection, that it tends to be higher in studies with fewer animals per group because detection power falls with sample size, and that observed response rates at doses meeting NOAEL criteria run about 5-20 percent above control rather than zero.
- Remove any one of them and what remains is merely a level at which nothing was noticed, which is a far weaker object than it looks.
Verification¶
This reference passed the adversarial substantiation pipeline: it was checked to exist and to support the claim it is attached to. See how references were verified.
Registry ID ref:a75e2af67fa7 · see in the full table