The dominance theory of Haldane's rule¶
Turelli, & Orr. (1995). The dominance theory of Haldane's rule. Genetics.
Cited by¶
1 citation across 1 artifact.
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Domain-specific¶
- Haldane's Rule
- The dominance hypothesis — currently the most empirically supported — holds that Dobzhansky-Muller incompatibilities accumulating on the X chromosome are expressed in full in the hemizygous XY sex, because the single X has no homologous allele to mask the incompatibility, whereas in the XX sex a dominant wild-type allele on the second X can buffer the effect
This sourceThe dominance theory of Haldane's rule, on which partially recessive X-linked incompatibilities are expressed more strongly in the hemizygous XY hybrid sex than in the XX sex.
Supported in partVerified against the publisher's abstract
“the XY sex suffers more than the XX because X-linked alleles causing postzygotic isolation tend to have greater cumulative effects when hemizygous than when heterozygous, even though the XX sex carries twice as many such alleles”
- The dominance hypothesis — currently the most empirically supported — holds that Dobzhansky-Muller incompatibilities accumulating on the X chromosome are expressed in full in the hemizygous XY sex, because the single X has no homologous allele to mask the incompatibility, whereas in the XX sex a dominant wild-type allele on the second X can buffer the effect
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Registry ID ref:a9a844bdf6b6 · see in the full table