The long-term effects of exposure to low doses of lead in childhood¶
Needleman, H. L., Schell, A., Bellinger, D., Leviton, A., & Allred, E. N. (1990). The long-term effects of exposure to low doses of lead in childhood: an 11-year follow-up report. New England Journal of Medicine, 322(2), 83-88.
Cited by¶
1 citation across 1 artifact.
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Primes¶
- Bioaccumulation
- Lead body burden in children from chronic low-level dust exposure: Lead is a ubiquitous heavy metal with elimination half-life in blood ~30 days but much longer in bone (~20 years), and the long-term neurodevelopmental consequences of low-level childhood exposure were established by Needleman, Schell, Bellinger, Leviton, and Allred (1990) in their NEJM follow-up of children whose dentine lead levels were measured a decade earlier.
This sourceLandmark follow-up showing low-level childhood lead exposure (dentine lead) produces persistent neurobehavioral deficits — body burden, not current ambient lead, drives harm.
Supported in partVerified against the work's full text
This NEJM 11-year follow-up links childhood dentin lead to persistent neurobehavioral and academic deficits in young adults; it gives no blood or bone half-life data for lead.
“we found that the associations reported earlier between lead and children's academic progress and cognitive functioning persisted into young adulthood.”
- Lead body burden in children from chronic low-level dust exposure: Lead is a ubiquitous heavy metal with elimination half-life in blood ~30 days but much longer in bone (~20 years), and the long-term neurodevelopmental consequences of low-level childhood exposure were established by Needleman, Schell, Bellinger, Leviton, and Allred (1990) in their NEJM follow-up of children whose dentine lead levels were measured a decade earlier.
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