Single-Cell Responses in Striate Cortex of Kittens Deprived of Vision in One Eye.¶
Wiesel, T. N., & Hubel, D. H. (1963). Single-Cell Responses in Striate Cortex of Kittens Deprived of Vision in One Eye. Journal of Neurophysiology, 26(6), 1003-1017.
Cited by¶
2 citations across 2 artifacts.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Pruning
- The essential grow-then-prune ordering is on display: one cannot prune a not-yet-grown cortex (there is no surplus to select from), and one cannot reach the mature specialized wiring by growing it directly, because the activity signal that identifies the right subset only exists once the surplus is in place and being driven by experience — the classic demonstration being monocular deprivation, where closing one eye biases the activity signal and the deprived eye's connections are pruned away.
This sourceThe monocular-deprivation experiments showing a biased activity signal prunes the deprived eye's connections.
- The essential grow-then-prune ordering is on display: one cannot prune a not-yet-grown cortex (there is no surplus to select from), and one cannot reach the mature specialized wiring by growing it directly, because the activity signal that identifies the right subset only exists once the surplus is in place and being driven by experience — the classic demonstration being monocular deprivation, where closing one eye biases the activity signal and the deprived eye's connections are pruned away.
- Readiness Window
- The cortical critical period for monocular deprivation makes this concrete: suturing one eye closed during a developmentally bounded interval produces permanent loss of cortical responsiveness to that eye even after reversal, while the same procedure on an adult produces full recovery
This sourceDemonstrates that monocular deprivation during a critical period produces permanent loss of cortical responsiveness, absent in adults.
- The cortical critical period for monocular deprivation makes this concrete: suturing one eye closed during a developmentally bounded interval produces permanent loss of cortical responsiveness to that eye even after reversal, while the same procedure on an adult produces full recovery
Verification¶
This reference passed the adversarial substantiation pipeline: it was checked to exist and to support the claim it is attached to. See how references were verified.
Registry ID ref:b6b0de7fa878 · see in the full table