Surviving Sepsis Campaign¶
Rhodes, A., Evans, L. E., Alhazzani, W., Levy, M. M., Antonelli, M., Ferrer, R., Kumar, A., et al. (2017). Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Intensive Care Medicine, 43(3), 304-377.
Cited by¶
3 citations across 3 artifacts.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Evidence-Latency Window
- Clinical diagnostics: a treatment must start within an hour (sepsis, stroke, anaphylaxis) while the confirmatory culture takes days; the standard catalogue is exactly the prime's — faster bedside tests, longer observation when safe, empirical-treatment-then-narrow protocols, lower-fidelity proxy markers.
This sourceMandates empirical broad-spectrum antibiotics within an hour with de-escalation once cultures return, plus lactate as a rapid proxy — the decouple-and-revise and proxy-substitution moves.
Supported in partVerified against the work's full text
The guideline supports sepsis treatment within an hour, empiric-then-narrow antibiotics and lactate as a surrogate, but not the 'exactly' matching four-part catalogue or anaphylaxis.
“We recommend that administration of IV antimicrobials be initiated as soon as possible after recognition and within 1 h for both sepsis and septic shock”
- Clinical diagnostics: a treatment must start within an hour (sepsis, stroke, anaphylaxis) while the confirmatory culture takes days; the standard catalogue is exactly the prime's — faster bedside tests, longer observation when safe, empirical-treatment-then-narrow protocols, lower-fidelity proxy markers.
- Rules Of Engagement
- Law enforcement: use-of-force policies bounding officer discretion through the same conditional structure of graduated steps and conditions. Content moderation: platform policies specifying what counts as a violation, what action is permitted at each severity, and when escalation is required. Customer-support escalation: tier-1 agents permitted to refund up to a limit without approval and required to escalate beyond it. Clinical protocols: standing orders and code-blue, sepsis, and triage protocols that permit specified actions for specified presentations without prior physician consultation.
This sourceCodifies sepsis bundles as standing orders permitting specified actions (cultures, fluids, antibiotics) on threshold criteria, with deliberate tolerance of false positives over delayed treatment.
Supported in partVerified against the work's full text
The guideline supplies the sepsis-protocol example: fixed, pre-specified actions triggered by a sepsis presentation and a call for protocol development, but only for sepsis.
“we recommend that initial fluid resuscitation begin with 30 mL/kg of crystalloid within the first 3 h. This fixed volume of fluid enables clinicians to initiate resuscitation while obtaining more specific information about the patient”
- Law enforcement: use-of-force policies bounding officer discretion through the same conditional structure of graduated steps and conditions. Content moderation: platform policies specifying what counts as a violation, what action is permitted at each severity, and when escalation is required. Customer-support escalation: tier-1 agents permitted to refund up to a limit without approval and required to escalate beyond it. Clinical protocols: standing orders and code-blue, sepsis, and triage protocols that permit specified actions for specified presentations without prior physician consultation.
- Threshold-Triggered Rule Activation
- Environmental and occupational regulation. A monitoring station crossing a concentration limit, or a cumulative-exposure monitor crossing a regulatory threshold, activates advisories, restrictions, or shutdown procedures while the underlying quantity drifts continuously. Healthcare. Vital-sign criteria crossing a sepsis-protocol threshold page the response team and initiate a care bundle; biomarker thresholds activate diagnostic categories and treatment eligibility.
This sourceDefines threshold criteria (e.g., qSOFA/SIRS) that trigger a time-boxed sepsis care bundle, the clinical instance of a dormant rule activating on a crossing.
Supported in partVerified against the work's full text
The SSC 2016 guideline links formal sepsis screening to bundled, time-limited care; it sets no vital-sign thresholds or paging step and says biomarkers are only supportive.
“Sepsis performance improvement programs can be aimed at earlier recognition of sepsis via a formal screening effort and improved management of patients once they are identified as being septic.”
- Environmental and occupational regulation. A monitoring station crossing a concentration limit, or a cumulative-exposure monitor crossing a regulatory threshold, activates advisories, restrictions, or shutdown procedures while the underlying quantity drifts continuously. Healthcare. Vital-sign criteria crossing a sepsis-protocol threshold page the response team and initiate a care bundle; biomarker thresholds activate diagnostic categories and treatment eligibility.
Verification¶
Does it exist? Confirmed. This work's DOI resolves to a registered record, which fixes its identity. That is all it fixes.
Does it back the claim? Read against the text for 3 of 3 citations: 3 supported in part. Each verdict is shown under its citation below, with what in the work backs the sentence.
Support is checked per citation rather than per work — the same source can be cited soundly in one article and wrongly in another. Per-citation recording began recently, so a citation with no recorded check is a gap in the record rather than evidence it went unchecked.
See how references were verified.
Registry ID ref:b9109f21935f · see in the full table