Surviving Sepsis Campaign¶
Rhodes, A., Evans, L. E., Alhazzani, W., Levy, M. M., Antonelli, M., Ferrer, R., Kumar, A., et al. (2017). Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Intensive Care Medicine, 43(3), 304-377.
Cited by¶
3 citations across 3 artifacts.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Evidence-Latency Window
- Clinical diagnostics: a treatment must start within an hour (sepsis, stroke, anaphylaxis) while the confirmatory culture takes days; the standard catalogue is exactly the prime's — faster bedside tests, longer observation when safe, empirical-treatment-then-narrow protocols, lower-fidelity proxy markers.
This sourceMandates empirical broad-spectrum antibiotics within an hour with de-escalation once cultures return, plus lactate as a rapid proxy — the decouple-and-revise and proxy-substitution moves.
- Clinical diagnostics: a treatment must start within an hour (sepsis, stroke, anaphylaxis) while the confirmatory culture takes days; the standard catalogue is exactly the prime's — faster bedside tests, longer observation when safe, empirical-treatment-then-narrow protocols, lower-fidelity proxy markers.
- Rules Of Engagement
- Law enforcement: use-of-force policies bounding officer discretion through the same conditional structure of graduated steps and conditions. Content moderation: platform policies specifying what counts as a violation, what action is permitted at each severity, and when escalation is required. Customer-support escalation: tier-1 agents permitted to refund up to a limit without approval and required to escalate beyond it. Clinical protocols: standing orders and code-blue, sepsis, and triage protocols that permit specified actions for specified presentations without prior physician consultation.
This sourceCodifies sepsis bundles as standing orders permitting specified actions (cultures, fluids, antibiotics) on threshold criteria, with deliberate tolerance of false positives over delayed treatment.
- Law enforcement: use-of-force policies bounding officer discretion through the same conditional structure of graduated steps and conditions. Content moderation: platform policies specifying what counts as a violation, what action is permitted at each severity, and when escalation is required. Customer-support escalation: tier-1 agents permitted to refund up to a limit without approval and required to escalate beyond it. Clinical protocols: standing orders and code-blue, sepsis, and triage protocols that permit specified actions for specified presentations without prior physician consultation.
- Threshold-Triggered Rule Activation
- Environmental and occupational regulation. A monitoring station crossing a concentration limit, or a cumulative-exposure monitor crossing a regulatory threshold, activates advisories, restrictions, or shutdown procedures while the underlying quantity drifts continuously. Healthcare. Vital-sign criteria crossing a sepsis-protocol threshold page the response team and initiate a care bundle; biomarker thresholds activate diagnostic categories and treatment eligibility.
This sourceDefines threshold criteria (e.g., qSOFA/SIRS) that trigger a time-boxed sepsis care bundle, the clinical instance of a dormant rule activating on a crossing.
- Environmental and occupational regulation. A monitoring station crossing a concentration limit, or a cumulative-exposure monitor crossing a regulatory threshold, activates advisories, restrictions, or shutdown procedures while the underlying quantity drifts continuously. Healthcare. Vital-sign criteria crossing a sepsis-protocol threshold page the response team and initiate a care bundle; biomarker thresholds activate diagnostic categories and treatment eligibility.
Verification¶
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