The Structure of the Potassium Channel¶
Doyle, D. A., Cabral, J. M., Pfuetzner, R. A., Kuo, A., Gulbis, J. M., Cohen, S. L., Chait, B. T., et al. (1998). The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity. Science, 280(5360), 69-77.
Cited by¶
1 citation across 1 artifact.
Each citation links to the sentence it supports in the citing article.
Primes¶
- Permeability
- The selectivity profile is exquisite and type-selective: a potassium channel passes K\(^+\) a thousand-fold more readily than Na\(^+\), by matching pore geometry and charge to the target ion — selectivity by kind, engineered into the pathway.
This sourceStructural basis of the potassium channel's selectivity filter, which coordinates K+ but excludes the smaller Na+ via pore geometry and carbonyl chemistry.
- The selectivity profile is exquisite and type-selective: a potassium channel passes K\(^+\) a thousand-fold more readily than Na\(^+\), by matching pore geometry and charge to the target ion — selectivity by kind, engineered into the pathway.
Verification¶
This reference passed the adversarial substantiation pipeline: it was checked to exist and to support the claim it is attached to. See how references were verified.
Registry ID ref:bb381231d58a · see in the full table